Function:
Betadex Sulfobutyl Ether Sodium is a new type of excipients, which is a sulfonic acid derivative of anionic, highly water-soluble cyclodextrin. It can be well included with molecules to form non-covalent complexes, which improves the stability, water solubility, safety and effectively improves the biological activity of the molecule. It has low nephrotoxicity and can alleviate the hemolysis. Control the release rate.
Despcription
SBE-β-CD is a high water-soluble anionic cyclodextrin derivative. It can easily form non-covalent inclusion complexes with drug molecules, thus it has the good performances in enhancing drug stability, solubility and safety, reducing drug toxicity and hemolysis, covering up bad smell, and controlling drug release rate.
Application
SBE-β-CD has been used in injection, oral, nasal and eye medication. Modification by charged functional units can improve the binding affinity of cyclodextrins for oppositely charged guests, so it has a special affinity for drugs with nitrogen elements.
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